Recent Sefton Lab Papers
Schulte, R. J., and Sefton, B. M. (2003) Inhibition of the activity of Src and Abl tyrosine protein kinases by the binding of the Wiskott-Aldrich Syndrome Protein. Biochemistry 42:9424-9430.
Kjellen, P., Amdjadi ,K., Lund, T. C., Medveczky, P. G., Sefton, B. M. (2002) The herpesvirus saimiri Tip484 and Tip488 proteins both stimulate Lck tyrosine protein kinase activity in vivo and in vitro. Virology 297:281-288. (Abstract)
Chiang, G. G., and Sefton, B. M. (2001) Specific dephosphorylation of the Lck tyrosine protein kinase at Tyr 394 by the SHP-1 tyrosine phosphatase. J. Biol. Chem. 276:23173-23178. (Link to text of this paper)
Hartley, D. A, Amdjadi, K., Hurley, T. R., Lund, T. C., Medveczky, P. G., and Sefton, B. M. (2000) Activation of the Lck Tyrosine Protein Kinase by the Herpesvirus Saimiri Tip Protein Involves Two Binding Interactions. Virology 276:339-348. (Link to text of this paper)
Amdjadi, K., and Sefton, B. M. (2000) Ultraviolet Light-Induced Stimulation of the JNK MAP Kinase in the Absence of Src Family Tyrosine Kinase Activation. J. Biol. Chem. 275: 22520-22525. (Link to text of this paper)
Chiang, G. C., and Sefton, B. M. (2000) Phosphorylation of a Src kinase at the autophosphorylation site in the absence of Src kinase activity. J. Biol. Chem. 275: 6055-6058. [Link to the text of this paper]
Lund, T. C., Coleman, C., Horvath, E., Sefton, B. M., Jove, R., Medveczky, M. M., Medveczky, P. G. (1999) The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity. Cell Signal 11:789-796. [Abstract]
Hartley, D. A., Hurley, T. R., Hardwick, J. S., Lund, T. C., Medveczky, P. G., and Sefton, B. M. (1999) Activation of the Lck tyrosine protein kinase by the binding of the Tip protein of herpesvirus saimiri does not require tyrosine phosphorylation of the Lck protein. J. Biol. Chem 274:20056--20059. [Link to the text of this paper]
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