William A. Alaynick, Ph.D.
Research Associate
Email: alaynick@salk.edu
Extension: x1187
2006 Ph.D. Biomedical Sciences, University of California, San Diego
and Howard Hughes Medical Institute, Salk Institute for Biological Studies
Ronald M. Evans, Ph.D., Thesis Advisor
La Jolla, CA
2001 B.A. History and Science, University of Washington, Seattle, WA
2006-present
Research Associate
Gene Expression Laboratory, Salk Institute for Biological Studies
La Jolla, CA
Samuel L. Pfaff, Ph.D., Supervisor
1998-2001
Research Technician I
Howard Hughes Medical Institute, Department of Biochemistry
University of Washington
Seattle, WA
Richard D. Palmiter, Ph.D., Supervisor
2006
Demonstrator
Aaron Price Fellows Program
2004
Mentor
Salk Institute Summer Student Program
2002-present
Instructor
Salk Mobile Sciences Lab
Ellen Potter, Ph.D., Supervisor
1996-1998
Emergency Medicine Services
University of Washington Medical Center
Mickey S. Eisenberg, M.D. Ph.D. M.P.H., Preceptor
2005
Biomedical Sciences, UCSD: Best Poster
2004
Salk Society of Research Fellows: Research Presentations
2003-2005
Training Program in Basic and Clinical Genetics
Alaynick WA, Kondo RP, Xie W, He W, Dufour CR, Downes M, Jonker JW, Giles WR, Naviaux RK, Giguere V, Evans RM. ERRγ Directs and Maintains the Transition to Oxidative Metabolism in the Post-Natal Heart. Cell Metab. 2007 Jul 11;6(1):13-24.
Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M, Giguère V. Genome–wide orchestration of cardiac functions by orphan nuclear receptors ERRα and γ. Cell Metab. 2007 May;5(5):345-56.
Lee C-H, Kang K, Mehl IR, Nofsinger R, Alaynick WA, Chong L-W, Rosenfeld JM and Evans RM. Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2434-9.
Mizutani A, Wang L, Rajan H, Vig PJ, Alaynick WA, Thaler JP, Tsai CC. Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1. EMBO J. 2005 Sep 21;24(18):3339-51.
Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A Nuclear Receptor Atlas: Macrophage Activation. Mol Endocrinol. 2005 Oct;19(10):2466-77.
Hnasko TS, Szczypka MS, Alaynick WA, During MJ, Palmiter RD. A role for dopamine in feeding responses produced by orexigenic agents. Brain Res. 2004 Oct 15;1023(2):309-18.
Szczypka MS, Rainey MA, Kim DS, Alaynick WA, Marck BT, Matsumoto AM, Palmiter RD. Feeding behavior in dopamine-deficient mice. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12138-43.
Alaynick WA, Kondo R, Dufour C, Giles WR, Giguere V, Evans RM. Loss of ERR3 Results in Cardiac Conduction Defects in Mouse. Keystone Symposium Orphan Brothers, 2006
Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A Nuclear Receptor Atlas: Macrophage Activation. Keystone Symposium PPAR/LXR, 2005
Alaynick WA, Meyers CP, Xie W, Pfaff SL, Evans RM. Estrogen-related Receptor 3 Knockout Mice Display Motor Abnormalities Contributing to Perinatal Lethality. Keystone Symposium Orphan Brothers, 2004