Karen Lettieri
Research Assistant
Email: lettieri@salk.edu
Extension: x2019
1996 B.S. Biology, University of California, San Diego
1996-present
Research Assistant, The Salk Institute, La Jolla, CA
Samuel L. Pfaff, Ph.D., Supervisor
1995-1996
Undergraduate Lab Assistant, The Burnham Institute, La Jolla, CA
Terumi Kohwi, Ph.D., Supervisor
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O, Trono D, Pfaff SL. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 2012 Jul 5;487(7405):57-63.
Bonanomi D, Chivatakarn O, Bai G, Abdesselem H, Lettieri K, Marquardt T, Pierchala BA, Pfaff SL. Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals. Cell. 2012 Feb 3;148(3):568-82.
Bai G, Chivatakarn O, Bonanomi D, Lettieri K, Franco L, Xia C, Stein E, Ma L, Lewcock JW, Pfaff SL. Presenilin-dependent receptor processing is required for axon guidance. Cell. 2011 Jan 7;144(1):106-18.
Macfarlan TS, Gifford WD, Agarwal S, Driscoll S, Lettieri K, Wang J, Andrews SE, Franco L, Rosenfeld MG, Ren B, Pfaff SL. Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes Dev. 2011 25:594-607.
Lee, S.-K. Jurata, L.W., Nowak, R., Lettieri, K., Pfaff, S.L., and Gill, G.N. (2004). The LIM domain-only protein LMO4 is required for neural tube closure. Mol. Cell. Neuro. 28: 205-14
Thaler, J. P., Koo, S. J., Kania, A., Lettieri, K., Andrews, S., Cox, C., Jessell, T. M., and Pfaff, S. L. (2004). A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron 41, 337-350.
Sharma, K., Leonard, A.E., Lettieri, K., and Pfaff, S.L. (2000). Genetic and epigenetic mechanisms contribute to motor neuron pathfinding. Nature 406: 515-519.
Thaler, J., Harrison, K., Sharma, K., Lettieri, K., Kehrl, J., and Pfaff, S.L. (1999). Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron 23: 675-68.
Sharma, K., Sheng, H., Lettieri, K., Li, H., Karavanov, A., Potter, S., Westphal, H., and Pfaff, S.L. (1998). LIM Homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell 95: 817-828.